Every Step Forward Begins with Hope

For people living with calpainopathy (LGMD2A/R1 & LGMDD4), every single day is a battle against progressive muscle wasting. Coalition to Cure Calpain 3 (C3) was founded in 2010 by patients who understand the urgent need for a cure. We set out to build a coalition of motivated stakeholders to drive research forward and to educate the global community about this rare disease.

Through a successful collaborative effort among patients, their families and friends, researchers, clinicians, advocates, and government and industry representatives, C3 has funded over $3 million, since our founding, to high-potential projects focused on finding a treatment, and ultimately a cure, for everyone living with limb-girdle muscular dystrophy types 2A/R1 & D4.

Every single dollar brings hope to our community.

Every single donation brings us one step closer to a scientific breakthrough.

Contribute by selecting the "Donate Now" button OR choose "Become a fundraiser" and create your own team to share your personal appeal with family and friends!

However you choose to give, your impact will be doubled during September (Muscular Dystrophy Awareness Month). Thanks to the generosity of SALT Service Co., every dollar donated from September 1 through September 30 (LGMD Awareness Day) will be matched, up to $10,000 total!

Partner with Team C3 & SALT Service Co. to power hope through life-changing calpainopathy research. Together, we can transform the future for every individual living with LGMD2A/R1 & LGMDD4!

One Month. One Mission. Endless Hope.

WE HAVE A MATCHING DONOR CHALLENGE FOR LGMD AWARENESS DAY! Partner with Team C3 & SALT Service Co. to power hope through life-changing research. Together, we can transform the future for everyone living with calpainopathy (LGMD2A/R1 & LGMDD4).