Help Fund the Next Breakthroughs in AUTS2 Research

Our goal is simple but ambitious: raise $300,000 to fund as many high-impact AUTS2 research projects as possible.

Thanks to a generous commitment from the founding family of the AUTS2 Research Collaborative, every donation made through September 8, 2026 will be matched dollar-for-dollar, doubling the impact of your gift.

September 8 marks the deadline for researchers around the world to submit proposals to our inaugural Research Catalyst Fund. Every matched donation received before then will help determine how many of these promising projects we can support.

Together, we have an extraordinary opportunity to accelerate the development of future treatments for AUTS2 syndrome.

Why This Matters

AUTS2 syndrome is a rare genetic condition that affects neurodevelopment and can impact communication, learning, movement, behavior, feeding, and many other aspects of daily life.

Today, there are no approved treatments that address the underlying biology of AUTS2.

But for the first time, researchers around the world are actively exploring multiple therapeutic strategies, including gene activation approaches designed to increase AUTS2 expression, drug repurposing opportunities, and other promising avenues for treatment development.

The challenge is no longer a lack of ideas.

The challenge is funding the research needed to determine which ideas can become treatments.

What Your Donation Could Fund

Earlier this year, the AUTS2 Research Collaborative launched its inaugural Research Catalyst Fund, inviting scientists around the world to submit proposals focused on advancing AUTS2 research and therapeutic development.

Proposed projects include:

Developing Potential AUTS2 Therapies
Researchers have proposed innovative approaches designed to increase AUTS2 expression, including cutting-edge CRISPR activation (CRISPRa) technologies that work by turning up activity of the AUTS2 gene without altering the underlying DNA sequence.

Building Better Research Models
Scientists are developing patient-derived stem cell and cellular models that can be used to study AUTS2 in the laboratory and evaluate potential therapies more rapidly and effectively.

Identifying Biomarkers for Future Clinical Trials
To bring treatments to patients, researchers need reliable ways to measure whether a therapy is working. Proposed projects aim to identify biomarkers that could help prepare the field for future clinical studies.

Accelerating Discovery
Other projects seek to better understand the fundamental biology of AUTS2, helping researchers identify new therapeutic targets and uncover opportunities for future drug development.

Every dollar raised will help determine how many promising AUTS2 research projects we can fund.

Join Us

Whether you donate, fundraise, share our campaign, or help spread awareness, you are helping fund the research needed to better understand AUTS2 and develop future treatments.

Together, we can accelerate research.

Together, we are AUTS2gether.

Matching Gift Opportunity

All donations made during the campaign will be matched dollar-for-dollar by the founding family of the AUTS2 Research Collaborative.

Your gift today will have twice the impact. Donate now and help us reach our $300,000 goal.

Other Ways to Give

Donations can also be made through a donor-advised fund (DAF), wire transfer, stock transfer, or other giving vehicles. If you would like instructions or have questions about making a tax-efficient gift, please contact us at info@auts2research.org.

AUTS2gether 2026 Campaign

⏳ Matching Gift Opportunity Extended Through September 8

Team Members