Three Researchers. Three Countries. One Global Mission.

We've started the research. Help us keep it going.

Research doesn't happen without funding. And for BBSOAS, that funding comes from our community.

BBSOAS (Bosch-Boonstra-Schaaf Optic Atrophy Syndrome) is an ultra-rare genetic condition caused by changes in the NR2F1 gene. For affected families, research offers hope for better understanding, improved care, and ultimately, treatments.

Just a few years ago, dedicated BBSOAS research was extremely limited. Today, thanks to the NR2F1 Foundation and our supporters, we are funding three postdoctoral researchers across the world:

🇩🇪 Germany – Heidelberg University: Investigating the NR2F1 gene and the biological mechanisms underlying BBSOAS.

🇮🇹 Italy – University of Turin: Advancing our understanding of NR2F1's role in brain development and function.

🇺🇸 United States – Cincinnati Children's Hospital: Building dedicated BBSOAS research capacity and advancing the science needed to work towards treatments.

This research is happening because our community is funding it. Without the Foundation's support, these dedicated research positions would not exist as they do today.

One global foundation. Research for every family.

BBSOAS knows no borders. Neither do we.

The NR2F1 Foundation supports families across more than 50 countries. While our researchers work in Germany, Italy, and the United States, their discoveries have the potential to benefit every family affected by BBSOAS, wherever they live.

This Giving Tuesday, help us sustain what we've started.

The Foundation has made significant multiyear commitments to fund these three researchers. This year, our priority isn't launching new projects. It's raising the funds needed to honor our existing commitments and keep this vital research moving forward.

Funding research is not a one-time investment. Our researchers need sustained support, and we cannot afford to lose the momentum our community has worked so hard to create.

We have the researchers. We have the expertise. We have the commitment. Now we need your support.

Every donation, large or small, helps us sustain global BBSOAS research and move closer to a future where treatments may be possible.

Please donate this Giving Tuesday. Together, we are making BBSOAS research possible. Together, we can keep it going.

What the NR2F1 Foundation Does

The NR2F1 Foundation is a global, patient-led nonprofit dedicated exclusively to families affected by rare NR2F1 gene variants.

Our vision is that every single family and individual living with rare NR2F1 variants will live a full and empowered life. Our mission is to empower families and individuals living with rare NR2F1 variants through education, advocacy and research.

Giving Tuesday 2026 - Three Researchers, One Global Mission

help Sustain life-changing research into BBSOAS around the world

Team Members