Whether a gift helps transform health data into better care, puts trusted knowledge into the hands of a family or clinician, or gives a promising idea the support it needs to become a real-world solution, every contribution helps create a healthier, brighter tomorrow.

This giving season, please consider donating to TLI.

What is TLI?

Behind every healthcare challenge is a person hoping for a better tomorrow. The Thought Leadership & Innovation Foundation (TLI) is a nonprofit that brings experts and organizations together to improve health and well-being. Through research, shared knowledge, and collaboration, we help turn promising ideas into meaningful progress for people and communities. This giving season, your generosity helps move that work forward.

Our Programs

Limb Loss and Preservation Registry (LLPR)

For millions of people living with limb loss, limb difference, or working to preserve a limb, better care begins with better information.

The Limb Loss and Preservation Registry (LLPR) is building the evidence base that clinicians, researchers, patients, and families need to better understand what works, for whom, and when. By bringing data together across the continuum of care, LLPR can help turn individual experiences into knowledge that supports better decisions and better outcomes. Your support helps TLI build the evidence needed to guide better care, keeping the people behind the data at the heart of the work.

Limb Outcomes Voice (LOV)

An important part of LLPR is Limb Outcomes Voice (LOV), which gives people living with limb loss, limb difference, or limb preservation a way to make their own experiences part of the story.

Through LOV, individuals can share and track what matters in daily life, including mobility, function, comfort, and emotional well-being. Those voices help create a fuller picture of outcomes and ultimately contribute to more patient-centered care. It brings everyday priorities, from comfort to quality of life, into the conversation about better care.

Autism Knowledge Gateway (AKG)

For families navigating autism, finding reliable healthcare information should not be another obstacle.

The Autism Knowledge Gateway (AKG) is a centralized, AI-enabled library and collaboration hub designed to make peer-reviewed autism research and trusted resources more accessible to families and healthcare professionals.

AKG is working to put credible medical knowledge closer to the people who need it, helping clinicians and families make more informed decisions about the health and well-being of autistic people.

Your gift helps turn an overwhelming world of information into something far more powerful: knowledge that can lead to better conversations, better care, and a better tomorrow.

Innovation Hub

A promising idea can open new possibilities for a person, a family, or an entire community. TLI’s Innovation Hub is designed to bring experts and partners together to develop those ideas into workable solutions. Its approach combines shared knowledge with planning, tools, and training to help projects move toward implementation. Your generosity helps TLI build the partnerships and capabilities that give promising ideas a path to meaningful impact.

Three projects. One mission. A world of possibility.

Give today to help TLI turn innovation into impact for the people and communities who need it.

Give the Gift of Possibility

TLI's Annual Giving 2026